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Online Hizmetlere Toplu BakışTurkish Journal of Pharmaceutical Sciences
Turk J Pharm Sci. 2016; 13(1): 77-83 | DOI: 10.5505/tjps.2016.43534 | |||
Antimicrobial Activity of Some Species from Pinaceae and CupressaceaeMüjde Eryılmaz1, Alev Tosun2, İbrahim Tümen31Ankara University, Faculty Of Pharmacy, Department Of Pharmaceutical Microbiology, Ankara, Turkey2Ankara University, Faculty Of Pharmacy, Department Of Pharmacognosy, Ankara, Turkey 3Bartın University, Faculty Of Forestry, Department Of Wood Chemistry, Bartın, Turkey The aim of this study was to determine the antimicrobial activities of ethereal extracts of some Pinaceae and Cupressaceae species collected from Turkey. The extracts from Pinus nigra Arn., P. brutia Ten., P. halepensis Mill., Abies equi-trojani (Asch. et Sint. ex Boiss.) Coode et Cullen, A. bornmulleriana Mattf., A. cilicica (Ant. et Kotschy) Carr., A. nordmanniana (Steven) Spach., Cedrus libani A. Rich. and Picea orientalis L. belong to Pinaceae family and Juniperus oxycedrus L. subsp. oxycedrus, J. foetidissima Willd., J. excelsa Bieb., J. phoenicea L., Cupressus sempervirens var. pyramidalis Nym. and C. sempervirens var. horizontalis (Mill.) Gord. belong to Cupressaceae family were examined against Staphylococcus aureus ATCC 25923, S. aureus ATCC 43300 (MRSA), Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae RSKK 574 and Candida albicans ATCC 10231. The disc diffusion method was used to determine the antimicrobial activities of these extracts. All the tested extracts, except A. bornmulleriana, C. libani and P. halepensis showed weak antibacterial activity against the various tested bacteria comparing with the standards. Nevertheless, no antifungal activity was observed against C. albicans in all extracts. It was concluded that the tested extracts did not show promising antimicrobial activity against tested microorganisms. However, this is the first comprehensive investigation on the evaluation of antimicrobial activities on ethereal extracts of these species. Keywords: Antimicrobial, Cupressaceae, Extract, PinaceaePinaceae and Cupressaceae Familyalarına Ait Bazı Türlerin Antimikrobiyal AktivitesiMüjde Eryılmaz1, Alev Tosun2, İbrahim Tümen31Ankara University, Faculty Of Pharmacy, Department Of Pharmaceutical Microbiology, Ankara, Turkey2Ankara University, Faculty Of Pharmacy, Department Of Pharmacognosy, Ankara, Turkey 3Bartın University, Faculty Of Forestry, Department Of Wood Chemistry, Bartın, Turkey Bu çalışmanın amacı, Türkiye’den toplanan Pinaceae ve Cupressaceae familyalarına ait bazı türlerin, eterli ekstrelerinin antimikrobiyal aktivitelerinin araştırılmasıdır. Pinaceae familyasına ait olan Pinus nigra Arn., P. brutia Ten., P. halepensis Mill., Abies equi-trojani (Asch. et Sint. ex Boiss.) Coode et Cullen, A. bornmulleriana Mattf., A. cilicica (Ant. et Kotschy) Carr., A. nordmanniana (Steven) Spach., Cedrus libani A. Rich. ve Picea orientalis L. türlerinin ve Cupressaceae familyasına ait olan Juniperus oxycedrus L. subsp. oxycedrus, J. foetidissima Willd., J. excelsa Bieb., J. phoenicea L., Cupressus sempervirens var. pyramidalis Nym. ve C. sempervirens var. horizontalis (Mill.) Gord. türlerinin ekstreleri, Staphylococcus aureus ATCC 25923, S. aureus ATCC 43300 (MRSA), Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae RSKK 574 ve Candida albicans ATCC 10231’a karşı disk difüzyon yöntemi ile araştırılmıştır. A. bornmulleriana, C. libani ve P. halepensis’in test mikroorganizmaları üzerinde antimikrobiyal aktivitesi saptanmazken; diğerlerinin çeşitli bakterilere karşı zayıf antibakteriyel etki gösterdiği ancak C. albicans’a karşı aktivite göstermediği belirlenmiştir. Bu çalışma, bu türlerin eterli ekstrelerinin antimikrobiyal aktivitelerinin değerlendirilmesi üzerine yapılan ilk çalışma olması nedeniyle önem taşımaktadır. Anahtar Kelimeler: Antimikrobiyal, Cupressaceae, Ekstre, PinaceaeMüjde Eryılmaz, Alev Tosun, İbrahim Tümen. Antimicrobial Activity of Some Species from Pinaceae and Cupressaceae. Turk J Pharm Sci. 2016; 13(1): 77-83 Corresponding Author: Müjde Eryılmaz, Türkiye |
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