Online Makale
Online Hizmetlere Toplu BakışSisli Etfal Tip Bülteni
Med Bull Sisli Etfal Hosp. 2020; 54(2): 169-175 | DOI: 10.14744/SEMB.2018.45077 | |||
Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving InjuriesErkan Yuce1, Kamuran Zeynep Sevim2, Medeni Volkan Kiyak3, Kemalettin Yildiz4, Daghan Dagdelen5, Fatih Irmak2, Semra Karsidag2, Ulkan Kilic41Department of Plastic Reconstructive and Aesthetic Surgery, Kirikkale Yuksek Ihtisas Hospital, Kirikkale, Turkey2Department of Plastic Reconstructive and Aesthetic Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey 3MVK Aesthetic Clinic, İstanbul, Turkey 4Department of Plastic Reconstructive and Aesthetic Surgery, Bezmialem Foundation University, Istanbul, Turkey 5Department of Plastic Reconstructive and Aesthetic Surgery, Trakya University Faculty of Medicine, Edirne, Turkey Objectives: Degloving hand injuries have generally been viewed as among the most difficult of injuries to manage due to the extensive nature of associated damage. The traditional approach to the circumferentially degloved segment of problematic flap viability has been to resuture the flap and to wait and see. However, the waiting period or the specific hemorheological protocol remains uncertain. The purpose of this study is to acknowledge if Sivelestat, known to ameliorate ischemia reperfusion injury, enhances the survival of avulsed flaps in a hind limb degloving model of rats and to compare Sivelestat’s effects to Pentoxifylline. Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving InjuriesErkan Yuce1, Kamuran Zeynep Sevim2, Medeni Volkan Kiyak3, Kemalettin Yildiz4, Daghan Dagdelen5, Fatih Irmak2, Semra Karsidag2, Ulkan Kilic41Department of Plastic Reconstructive and Aesthetic Surgery, Kirikkale Yuksek Ihtisas Hospital, Kirikkale, Turkey2Department of Plastic Reconstructive and Aesthetic Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey 3MVK Aesthetic Clinic, Istanbul, Turkey 4Department of Plastic Reconstructive and Aesthetic Surgery, Bezmialem Foundation University, Istanbul, Turkey 5Department of Plastic Reconstructive and Aesthetic Surgery, Trakya University Faculty of Medicine, Edirne, Turkey Objectives: Degloving hand injuries have generally been viewed as among the most difficult of injuries to manage due to the extensive nature of associated damage. The traditional approach to the circumferentially degloved segment of problematic flap viability has been to resuture the flap and to wait and see. However, the waiting period or the specific hemorheological protocol remains uncertain. This study aims to acknowledge if Sivelestat, known to ameliorate ischemia-reperfusion injury, enhances the survival of avulsed flaps in a hind limb degloving model of rats and to compare Sivelestat’s effects to Pentoxifylline. Erkan Yuce, Kamuran Zeynep Sevim, Medeni Volkan Kiyak, Kemalettin Yildiz, Daghan Dagdelen, Fatih Irmak, Semra Karsidag, Ulkan Kilic. Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving Injuries. Med Bull Sisli Etfal Hosp. 2020; 54(2): 169-175 Sorumlu Yazar: Erkan Yuce, Türkiye |
|