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Med Bull Sisli Etfal Hosp. 1997; 31(1): 19-22 | |||
Kronik Renal Yetersizlikli Hastalarda Hemodiyalizin Plazma Endotilin-1 Düzeyi Üzerine EtkisiGürkan Yurteri, Hakkı Arıkan, Nurgül Güven, Yalçın Özbahar, Aydoğan ÖbekŞişli Etfal Hastanesi Nefroloji KliniğiAMAÇ: Bu çalışma, kronik renal yetersizlikli hastalarda hemodiyalizin plazma endotelin-1 düzeyi üzerine olan etkisini araştırmak amacıyla planlandı. The Effect of Hemodialysis on Levels of Endothelin-1 in Cases With Chronic Renal FailureGürkan Yurteri, Hakkı Arıkan, Nurgül Güven, Yalçın Özbahar, Aydoğan ÖbekŞişli Etfal Hastanesi Nefroloji KliniğiOBJECTIVE: This study is planned to investigate the effect of hemodialysis on levels ol Endothelin-1 (ET-1) in cases with chronic renal failure. STUDY DESIGN: 20 patients who have chronic renalfailure were included to our study. 10 of them (Group A) were treated with hemodialysis, 10 of them (Grup B) weren' t. As for the control group 10 healty people selected. The levels of plasma ET-1 determined with the method ol radio immun assay (RIA). RESULTS: The levels of plasma ET-1 was significantly higher patients who have chronic renal failure than healty people (p<0.001 ), but no significant changes was frıurıd between Group A and Group B (p>0.05). CONCLUSION: These results suggested that hemodialysis has no effects on the levels of plasma ET -1. Also no significant changes was found between patients who have high blood pressure and normal blood pressure on the levels of plasma ET -1. This study also suggested that only uremia may he the cause of high levels of plasma ET-. Keywords: Endothelin-1, chronic renal failure, hemodialysis.Gürkan Yurteri, Hakkı Arıkan, Nurgül Güven, Yalçın Özbahar, Aydoğan Öbek. The Effect of Hemodialysis on Levels of Endothelin-1 in Cases With Chronic Renal Failure. Med Bull Sisli Etfal Hosp. 1997; 31(1): 19-22 Sorumlu Yazar: Gürkan Yurteri, Türkiye |
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