İstanbul Kuzey Klinikleri Dergisi

[North Clin Istanb]
North Clin Istanb. 2014; 1(3): 191-193 | DOI: 10.14744/nci.2014.36036  

Dramatic response in the dependency to transfusion after low doses of lenalidomide treatment in a 5q-syndrome patient: a case report

Mehmet Hilmi Dogu, Ismail Sarı, Sibel Hacıoglu, Ali Keskin
Department Of Hematology, Pamukkale University Faculty Of Medicine, Denizli, Turkey

5q-syndrome is a special subgroup of myelodysplastic syndrome in terms of follow-up and treatment. Lenalidomide is an immunomodulatory drug that is frequently used in the treatment of multiple myeloma. Some clinical studies have shown that lenalidomide treatment is effective in 5q syndrome and significantly decreases the transfusion dependency in these patients. In this paper, we would like to share a dramatic response of lowered transfusion dependency after treatment with low-dose lenalidomide in a patient who received myelodysplastic syndrome diagnosis and isolated 5q anomaly in our clinic.

Keywords: del(5q), Lenalidomide; myelodysplastic syndrome.


Mehmet Hilmi Dogu, Ismail Sarı, Sibel Hacıoglu, Ali Keskin. Dramatic response in the dependency to transfusion after low doses of lenalidomide treatment in a 5q-syndrome patient: a case report. North Clin Istanb. 2014; 1(3): 191-193

Sorumlu Yazar: Mehmet Hilmi Dogu, Türkiye


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