The incidetal detection of a sarcomatoid lung cancer by [18f] choline positron emission tomography/computed tomography

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Molecular Imaging and Radionuclide Therapy

The incidetal detection of a sarcomatoid lung cancer by [18f] choline positron emission tomography/computed tomography []

. Ahead of Print: MIRT-81594

The incidetal detection of a sarcomatoid lung cancer by [18f] choline positron emission tomography/computed tomography

Marco Rensi¹, Decio Capobianco¹, Fernando Di Gregorio¹, Laura Evangelista²
¹Nuclear Medicine Unit, Azienda Sanitaria Universitaria Integrata, Udine, ITALY
²Nuclear Medicine and Molecular Imaging Unit, Department of Medicine DIMED, University of Padua, Padua, Italy

A 79-year old man, treated for prostate cancer (PCa) in 2018 with concurrent hormone therapy and radical radiotherapy (RT), was given metastasis-directed RT due to a skeletal progression of PCa in 2021. On [18F]-choline PET/CT for a biochemical recurrence (prostate-specific antigen level: 4.96 ng/mL), he showed a significant uptake in multiple skeletal lesions and a focal uptake in a left lung nodule. CT-guided biopsy revealed a sarcomatoid lung carcinoma. This case confirms that histopathological evaluation is mandatory in the event of a significant radiolabeled choline uptake in a single lung nodule.

Keywords: FluoroCholine, cancer, interpretation

Corresponding Author: Laura Evangelista, Italy

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