Atypical Variants of Mycosis Fungoides

Mycosis fungoides (MF) is the most common type of cutaneous T-Cell lymphoma and it is characterised by specific histological features. MF is in a spectrum of disorders which includes Sezary Syndrome (SS) and other cutaneous T-Cell lymphoma (CTCL) subtypes. Clinically and histopathologically it can imitate other T-cell mediated dermatosis hence making its diagnosis difficult. Due to different prognosis and difference in treatment strategies other subtypes of CTCL must be differentiated from MF. MF is a clinically indolent low-grade lymphoma which is seen in people aged between 55-60 and it’s seen more commonly in men (2: 1 ratio). Meanwhile other subtypes of MF like folliculotropic variant may show relatively a more aggressive course and our treatment strategy may differ.