Haydarpasa Numune Egitim ve Arastirma Hastanesi Tip Dergisi

[Haydarpasa Numune Med J]
Haydarpasa Numune Med J. 2022; 62(4): 476-479 | DOI: 10.14744/hnhj.2021.00236  

Highly Differentiated Follicular Carcinoma Arising from Struma Ovarii (Strumosis) Presenting as Pseudo-Meigs Syndrome with Elevated CA125 Level: A Case Report

Olcay Kurtulan1, Anıl Ertürk2, Nejat Özgül3, Alp Usubütün1
1Department of Pathology, Hacettepe University Faculty of Medicine, Ankara, Türkiye
2Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Türkiye
3Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Hacettepe University Faculty of Medicine, Ankara, Türkiye

A 75-year-old woman presented with the left ovarian mass, ascites, unilateral pleural effusion, and elevated CA125 levels. Clinical and radiological findings were highly suspicious for a malignancy. The patient underwent surgical excision of the uterus and infracolic omentum, and an intraoperative consultation was performed. Ovarian mass was diagnosed as “struma ovarii” and no other surgical procedure was performed. Histopatologic examination showed struma ovarii on the left ovary and bland-looking thyroid tissue implants on omentum and hernia sac. The patient diagnosed as “highly differentiated follicular carcinoma arising from struma ovarii” (HDFCO). No additional therapy was recommended to the patient and after a 53 months of follow-up, no recurrence was identified. HDFCO previously named strumosis is characterized by the presence of thyroid tissue in the peritoneal cavity with a bland morphology. Pseudo-Meigs syndrome with elevated serum CA125 levels in a 75-year-old lady is highly suspicious for malignancy, but HDFCO is an entity with a benign clinical course that shows the importance of intraoperative consultation. We describe the first case of HDFCO (strumosis) presenting as Pseudo-Meigs syndrome with elevated serum CA125 levels.

Keywords: CA125, pseudo-meigs’ syndrome, struma ovarii, strumosis.


Olcay Kurtulan, Anıl Ertürk, Nejat Özgül, Alp Usubütün. Highly Differentiated Follicular Carcinoma Arising from Struma Ovarii (Strumosis) Presenting as Pseudo-Meigs Syndrome with Elevated CA125 Level: A Case Report. Haydarpasa Numune Med J. 2022; 62(4): 476-479

Sorumlu Yazar: Olcay Kurtulan, Türkiye


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