Sinus Node Dysfunction in a Child After Developed by the Use of Topical Minoxidil

Minoxidil is a drug being widely used in alopecia topically and systemically. Various cardiovascular side-effects corresponding to this drug has been reported in the adults, and leastwise in the pediatric patients. A 9 year old girl, having been using topical minoxidil for 2 years due to alopecia; was directed to our clinic for cardiac assessment prior to commencing systemic minoxidil treatment. No meaningful finding was attained neither in the received history of the patient, and in her physical examination. In the holter examination of the patient with normal echocardiography and electrocardiography, 6 seconds long asystolia attack accompanied by syncope was observed. Upon being hospitalization, minoxidil treatment of the patient was quitted. During monitoring, syncope was not recurred in the patient, sinus node functions of whom were assessed transesophageally as normal. Taking the morbidity of permanent pacemaker implantation in the 9 years old pediatric patient, and the temporariness of the reason of sinus node dysfunction in the patient, the patient was not implanted with permanent pacemaker. The patient, who was monitored for ten days in the service she was hospitalized, and examinations of whom were completed meanwhile, is now monitored trouble-free as an outpatient in our clinic. Since such cardiac side-effects as tachycardia, pericardial effusion, myocardial infarction corresponding to minoxidil usage have been reported in the literature, and due to the presence of sinus arrest having developed in the introduced case likely in correspondence with minoxidil, cardiac attention has to be paid to the patients using minoxidil.