Assessment of vitamin D levels in patients with acute coronary syndrome

INTRODUCTION: In recent studies, vitamin D is claimed to have positive effects for acute coronary syndrome (ACS) by decreasing states that are accepted as important risk factors for ACS development such as endothelial damage, high blood pressure, insulin resistance, diabetes development and vascular inflammation.
METHODS: We have investigated the relation between ACS and plasma vitamin D levels in this study.
RESULTS: The study was conducted with a total number of 90 patients diagnosed with ACS and 50 individuals with normal coronary artery angiography. No significantly different plasma vitamin D levels of control group was detected compared to the patients with ACS (Mean=15,2±4,8 versus 15,3±6,3ng/ml, p>0.05). Significant difference related to smoking prevalence was detected between the two groups (52.8% versus 20%, p<0.01).
DISCUSSION AND CONCLUSION: We have concluded that Vitamin D insufficiency does not increase the risk for development of ACS significantly, after the corrections related to blood cholesterol elevation, smoking, diabetes, high blood pressure, family history. According to these results, there was no association between plasma level of vitamin D and the risk of development of ACS