Congenital primary hypothyroidism associated with the rare form of nonimmune hydrops fetalis

Sevil Arı Yuca¹, Yaşar Cesur, Ercan Kırımi¹, Şehabettin Sarı¹, Avni Kaya¹, Murat Doğan¹

We present a male newborn born with diffuse edema and ascites. A diagnosis of congenital primary hypothyroidism was made based on thyroid hormone levels of total T4 1.74 µg/dL, free T4 0.30 ng/dL and TSH >75 µIU/mL and thyroid hormone replacement therapy was initiated. At day 15 of therapy, the thyroid function tests of the patient reached normal limits, and his edema and ascites regressed. In this report we present a newborn case of hypothyroidism that was accompanied by nonhydrops fetalis. We want to emphasize that congenital hypothyroidism may present with severe symptoms such as hydrops.

Keywords: Hypothyroidis, hydrops fetalis, newborn

Sevil Arı Yuca, Yaşar Cesur, Ercan Kırımi, Şehabettin Sarı, Avni Kaya, Murat Doğan. Congenital primary hypothyroidism associated with the rare form of nonimmune hydrops fetalis. Eastern J Med. 2010; 15(1): 40-42

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