Beyoglu Eye Journal

Chickenpox Associated Retinitis and Occlusive Vasculitis in a Vaccinated Child: A Case Report and Literature Review [Beyoglu Eye J]
Beyoglu Eye J. 2022; 7(2): 143-149 | DOI: 10.14744/bej.2022.50490  

Chickenpox Associated Retinitis and Occlusive Vasculitis in a Vaccinated Child: A Case Report and Literature Review

Gökçen Özcan1, Emine Temel1, Nilufer Yalçındağ1, Erdal Ince2, Pınar Bingöl Kızıltunç1, Elif Ince3, Huban Atilla1
1Department of Ophthalmology, Ankara University, Ankara, Turkey
2Department of Pediatric Infectious Disease, Ankara University, Ankara, Turkey
3Department of Pediatric Hematology, Ankara University, Ankara, Turkey

Either retinitis and occlusive vasculitis are rare but vision threatening ocular complications of chickenpox in children. In this case report a 13-year-old girl who developed chickenpox 2 days before complaining with visual loss in her right eye is present-ed. She was vaccinated one dose of varicella zoster virus (VZV) vaccine when she was 12 months old. Best corrected visual acuity was counting fingers at 1.5 m in right eye. A subtle anterior segment inflammation and mild vitritis were observed. Fun-doscopic examination of right eye showed ischemia in paracentral macula and white foci of retinitis along the superotemporal branch of retinal vessels. She was hospitalized and intravenous acyclovir treatment at 3 × 10 mg/kg daily dose was started. Serum IgM and IgG for VZV were positive. Aqueous humor PCR test was also reported positive for VZV DNA. Oral meth-ylprednisolone was added at a dose of 64 mg/day at the 3rd day acyclovir treatment. Macular edema developed at 4th week of treatment and bevacizumab was administered intravitreally. After 3 injections retinal edema subsided completely. At 6-month follow-up retinal ischemia in superotemporal periphery was observed and photocoagulation was added to treatment.

Keywords: Chickenpox, macular edema, occlusive vasculitis, paracentral acute middle maculopathy, retinitis, single dose vaccine.


Gökçen Özcan, Emine Temel, Nilufer Yalçındağ, Erdal Ince, Pınar Bingöl Kızıltunç, Elif Ince, Huban Atilla. Chickenpox Associated Retinitis and Occlusive Vasculitis in a Vaccinated Child: A Case Report and Literature Review. Beyoglu Eye J. 2022; 7(2): 143-149

Corresponding Author: Gökçen Özcan, Türkiye


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